Low temperature coolant circulation pump is a low-temperature liquid circulation equipment that adopts mechanical refrigeration, and has the function of providing low-temperature liquid and low-temperature water bath. Combining rotary evaporators, vacuum freeze-drying ovens, circulating water vacuum pumps, magnetic stirrers, and other instruments for multifunctional low-temperature chemical reaction operations and drug storage. Low temperature coolant circulation pump can be matched with various instruments (rotary evaporator, fermentation tank, chemical reaction kettle, freeze-drying equipment, biopharmaceutical reaction kettle, etc.); Large cooling capacity and fast cooling speed greatly improve work efficiency; The flow rate of the local circulation pump can be adjusted or customized to meet the actual needs of different users; All models of this machine can be reasonably matched between low temperature and cooling capacity, low temperature and container capacity according to user requirements.